解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::The localisation and distribution of the cytoskeletal protein tubulin in the adult liver fluke Fasciola hepatica have been determined by an indirect immunofluorescence technique using a monoclonal antibody raised against beta-tubulin. Tubulin was demonstrated in the tegumental syncytium and in the tegumental cell bodi...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00931649
更新日期:1992-01-01 00:00:00
abstract::To quantify the effect of Nosema algerae (Microsporidia, Nosematidae) on the development of Plasmodium falciparum in Anopheles stephensi (Diptera, Culicidae), we carried out infection experiments under standardized laboratory conditions. Apart from a mean reduction of 69% in oocyst development, smaller numbers of oocy...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00931661
更新日期:1992-01-01 00:00:00
abstract::This experimental study on pigs was designed to simulate natural, long-term exposure to Ascaris suum under modern management conditions. Parasite kinetics were followed in pigs receiving A. suum eggs as repeated trickle inoculations at two dose levels beginning at a body weight of 25 kg until their slaughter at 90 kg ...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00931733
更新日期:1992-01-01 00:00:00
abstract::The metacercarial cyst walls of Paragonimus westermani, P. miyazakii, P. ohirai, and P. iloktsuenensis were examined using ultrastructural and histochemical techniques. The cyst walls of P. westermani, P. miyazakii, and P. ohirai were found to have five distinct layers, whereas the wall of P. iloktsuenensis had only t...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00931563
更新日期:1992-01-01 00:00:00
abstract::In an experiment including 8 groups of 15 mice, the effect of migrating Ascaris suum larvae in the lungs on the establishment and pathogenicity of aerosol exposure to Pasteurella multocida was investigated. Following aerosol exposure to P. multocida, mice with migrating A. suum in their lungs developed more severe pne...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00931575
更新日期:1992-01-01 00:00:00
abstract::The nervous system of Cysticercus cellulosae, the metacestode stage of the tapeworm Taenia solium, was delineated using histochemical methods for the localization of the enzyme markers; nonspecific esterase and acetylcholinesterase. The main features of the nervous system include a pair of cerebral ganglia, a circumce...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00936456
更新日期:1992-01-01 00:00:00
abstract::The susceptibility of two Venezuelan (YT and SM) and one Brazilian (BH) strain of Schistosoma mansoni to single oral doses of praziquantel (Pz; 250 or 500 mg/kg), oxamniquine (Ox; 40, 60, or 100 mg/kg) or to low-dose combinations of both drugs (33 mg/kg Pz and 25 mg/kg Ox; 66 mg/kg Pz and 12.5 mg/kg Ox; 250 mg/kg Pz a...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00931515
更新日期:1992-01-01 00:00:00
abstract::Trypanosoma cruzi proteinases are very likely involved in host-cell invasion. Physiological plasma-proteinase inhibitors from the macroglobulin (MG) family, among them alpha-2-macroglobulin (A2M), are found in tissues and in the plasma of mammals. By complexing to all classes of proteinases, MGs inhibit their action o...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00931729
更新日期:1992-01-01 00:00:00
abstract::Two soluble Toxoplasma gondii antigen preparations were compared using the immunoblotting technique. The first preparation, which is commonly employed in ELISA tests, corresponds to a lytic extract of the parasite. The second known as exo-antigen, has yielded good results in cell immunity research and is obtained from...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00931730
更新日期:1992-01-01 00:00:00
abstract::An in vitro system for studying the transformation of bloodstream forms of Trypanosoma brucei brucei into procylic (midgut) forms is described. In this system, transformation of the parasites was stimulated by Glossina morsitans morsitans midgut homogenates at 27 degrees C but not at 4 degrees C. The transformation-st...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00936174
更新日期:1992-01-01 00:00:00
abstract::Dimethyl sulfoxide (DMSO), commonly used for cryoprotection or for the solvation of cytoskeleton-modifying drugs, causes changes in the topology of the plasma membrane of the tegumental brush border in the tapeworm Hymenolepis diminuta; however, relatively long exposures of high concentrations are required. In tapewor...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00936184
更新日期:1992-01-01 00:00:00
abstract::An enzyme-linked immunosorbent assay (ELISA) was developed for the detection of Echinococcus coproantigens in fecal samples from dogs, dingoes or foxes infected with either E. granulosus or E. multilocularis. The ELISA was based on protein-A-purified polyclonal antibodies [anti-E. granulosus excretory/secretory (E/S) ...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00937088
更新日期:1992-01-01 00:00:00
abstract::Interferon-tau (IFN-tau) treatment of Trichinella spiralis-infected BALB/c mice was investigated. The therapeutic regimen consisted of daily intraperitoneal injection of 10(4) U murine IFN-tau for 7 days, starting at 2 weeks post-infection. Striated muscle samples (diaphragm, thigh) were collected at 4, 8 and 12 weeks...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00931641
更新日期:1991-01-01 00:00:00
abstract::A monoclonal antibody raised against membrane proteins of Toxoplasma gondii with molecular weights of 35 and 21 kDa also reacts strongly and "specifically" with surface antigens of Pneumocystis carinii with molecular weights of 394.2 and 69 kDa when used in a direct immunofluorescence antibody test, on the one hand, a...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00930914
更新日期:1991-01-01 00:00:00
abstract::In the present study, Diplectanum laubieri was redescribed from material obtained from wild and cultured fish. The population dynamics of D. aequans and D. laubieri under culture conditions was studied. The prevalence and mean intensity (average number of worms per parasitized fish) were 80.64% and 112 for D. aequans ...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00930906
更新日期:1991-01-01 00:00:00
abstract::Passive transfer of immunity using a mouse monoclonal IgE antibody against Schistosoma japonicum was found to be enhanced by heterologous helminth infections. BALB/c mice were infected with Toxocara canis or Nippostrongylus brasiliensis so as to induce eosinophilia prior to a challenge infection with S. japonicum. Rec...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00928681
更新日期:1991-01-01 00:00:00
abstract::A small type of Cryptosporidium oocysts was isolated from a naturally infected cat and its biological nature was investigated. In cats experimentally inoculated with Cryptosporidium oocysts, long-lasting shedding of the oocysts occurred after a prepatent period of 8-10 days, and a number of peaks of oocyst count appea...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00930864
更新日期:1991-01-01 00:00:00
abstract::Results obtained in experiments testing the efficacy of anti-procyclic-form rabbit sera on the development of homologous and heterologous stocks of Trypanosoma brucei brucei in Glossina morsitans morsitans indicated that this development was affected little, or not at all, by such sera. The absence of effect of anti-p...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00934382
更新日期:1991-01-01 00:00:00
abstract::In three different areas in northern Germany, hippoboscids were collected from red deer (Cervus elaphus). Typanosomatids were demonstrated in the midgut and hindgut of 9/37 Lipoptena cervi. The trypanosomatids were morphologically similar to vector forms of the subgenus Megatrypanum that had been found in tabanids at ...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00928691
更新日期:1991-01-01 00:00:00
abstract::The involvement of protein kinase C in the initiation of free oxygen radical generation by rat leukocytes in response to the nematode Nippostrongylus brasiliensis was investigated. Inhibitors of protein kinase C, trifluoperazine and 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine (H-7), inhibited free radical generatio...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00928421
更新日期:1991-01-01 00:00:00
abstract::Infections of Eimeria tenella in chicken embryos were used to compare the anticoccidial activity of ten drugs. The minimal inhibitory concentration (MIC) and minimal toxic concentration (MTC) were affected by the time of inoculation into the embryos and by the chemical nature of the compounds. Some compounds (nicarbaz...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00931020
更新日期:1991-01-01 00:00:00
abstract::Groups of five rats each were infected with metacercariae of Fasciola hepatica according to two experimental procedures. In the first experiment, they received 20 metacercariae 0, 1, 2 or 3 times at intervals of 4 weeks. In the second, both the inoculation dose and the interval between doses were varied. After the ani...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00931639
更新日期:1991-01-01 00:00:00
abstract::The distribution of actin filaments in the spermatogenic cells of Fasciola hepatica was determined using a fluorescent derivative of phalloidin. Actin was localised primarily in the region of separation of a secondary spermatogonium from a primary spermatogonium, in the inner faces at the centre of four-cell clusters ...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00935425
更新日期:1991-01-01 00:00:00
abstract::This report describes a technique for studying the adherence and growth of Giardia intestinalis trophozoites (strains PARIS/86/LCF/1, PARIS/86/LCF/2 and PARIS/88/LCF/8) using the human colon carcinoma cell line Caco2. Giardia trophozoites were cultured with Caco2 cells in a modified HSP3 culture medium. The biochemica...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00932566
更新日期:1990-01-01 00:00:00
abstract::The DNA content of the developmental stages within the life cycle of Babesia divergens was measured by means of fluorescence microscopy using the DNA-specific bisbenzimide Hoechst 33258. By comparing the mean relative fluorescence intensities, the assumption of sexual reproduction in the gut of the tick vector (Ixodes...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00930815
更新日期:1990-01-01 00:00:00
abstract::The authors previously reported that an extract from Zingiber officinale, traditionally eaten along with raw fish and used in traditional Chinese medicine, effectively destroyed Anisakis larvae in vitro. In this study, we analyzed the effective components of ginger rhizomes. Methanol extracts were fractionated after f...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00931082
更新日期:1990-01-01 00:00:00
abstract::Investigations by scanning and transmission electron microscopy and freeze-etching revealed that eyes of adult Rhipicephalus evertsi mimeticus consist of a lens and photoreceptor cells, which are separated by an acellular layer and the hypodermis. The lens contains numerous pore channels, which open beneath the epicut...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00933552
更新日期:1990-01-01 00:00:00
abstract::The localisation and distribution of the cholinergic, serotoninergic and peptidergic components of the nervous system of the frog-lung fluke Haplometra cylindracea have been determined by the application of standard enzyme cytochemical and immunocytochemical techniques to cryostat sections and whole-mount preparations...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00931056
更新日期:1990-01-01 00:00:00
abstract::Immunocytochemical studies using antibodies against various peptides were performed on Echinostoma caproni. Only the presence of substance P or a related peptide was clearly demonstrated in this digenetic trematode. In the central nervous system, substance P-immunoreactive neurons were few and constituted two populati...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00930963
更新日期:1989-01-01 00:00:00
abstract::The first description of an electron microscopic study of Trypanosoma corvi in the vector Ornithomyia avicularia is reported. There is a close association between vector and parasite in the midgut, ileum and rectum of the vector. The midgut distribution of parasites is determined by the peritrophic membrane, which con...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00931269
更新日期:1989-01-01 00:00:00
abstract::The effect of incubation of parasites (epimastigote and trypomastigote forms of Trypanosoma cruzi) or macrophages in the presence of tunicamycin (TM) or monensin (M) on the parasite-macrophage association was analysed. Treatment of the parasites with TM, a drug which interferes with the process of N-glycosylation of p...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00930829
更新日期:1989-01-01 00:00:00
abstract::The infectivity of Cryptosporidium muris (strain RN 66), originally isolated from the house rat (Iseki 1986), to various laboratory animals was studied by transmission experiments. After oral inoculation with 1 x 10(6) oocysts, mice, guinea pigs, rabbits, dogs, and cats all discharged endogenously produced oocysts in ...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00931279
更新日期:1989-01-01 00:00:00
abstract::In this study, the antigenic mosaic of the vesicular fluid (VF) and hydrosoluble cyst-wall extract (CWE) of T. crassiceps (Tc; harvested from mice) and T. saginata (Ts) metacestodes was analyzed by combined precipitation maps developed in single and bidimensional immunoelectrophoresis against the respective rabbit ant...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00931168
更新日期:1989-01-01 00:00:00
abstract::A total of 480 snails were collected from 3 habitats on the Mau Escarpment, Kenya, and were identified as Bulinus tropicus. Of the 351 snails examined alive in London, 75 were infected with Calicophoron microbothrium, 39 with C. microbothrium and Schistosoma bovis, 1 with S. bovis, 24 with other species of trematodes ...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00931134
更新日期:1989-01-01 00:00:00
abstract::In patients infected with Trichuris trichiura, large eggs as well as more typical eggs were frequently found in the feces; these large eggs have been attributed to human infection by T. vulpis. To clarify whether the female worms laying the large eggs were T. trichiura or T. vulpis, we examined the morphology of adult...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00930964
更新日期:1989-01-01 00:00:00
abstract::Trypanosoma acomys (Stercoraria, Trypanosomatidae) was studied in the laboratory-bred spiny mouse Acomys cahirinus. Only trypomastigotes were found in peripheral blood, whereas the thymus of experimentally infected A. cahirinus showed amastigote syncytial reproductive forms whose nuclei of nuclei ranged from 2 to 128....
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00930969
更新日期:1989-01-01 00:00:00
abstract::The effect on the tegument of adult Fasciola hepatica of incubation in the sodium ionophore monensin, the Na+/K+-ATPase inhibitor ouabain and ouabain pretreatment followed by monensin has been determined in vitro by scanning and transmission electron microscopy (SEM, TEM). With monensin incubation alone (1 x 10(-6) M)...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00931280
更新日期:1989-01-01 00:00:00
abstract::Immunoscreening of an adult Schistosoma mansoni cDNA expression library, using antibodies raised against purified adult worm tegumental surface membranes, identified a recombinant clone containing a 141-bp insert. Antibodies raised against the recombinant antigen bound specifically to the tegument of adult worms and i...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00931812
更新日期:1989-01-01 00:00:00
abstract::An endopeptidase specific to the Plasmodium falciparum erythrocytic schizont stage and to free merozoites was detected using the fluorogenic GlcA-Val-Leu-Gly-Lys(or Arg)-AEC substrate. The enzyme was purified by high performance liquid chromatography (HPLC); its optimal activity was around pH 7.5 and its isoelectric p...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00930972
更新日期:1989-01-01 00:00:00
abstract::The effect of the adult worms and migrating L1 larvae of Trichinella spiralis on the production of specific IgE antibodies was determined in BCF1 mice. To achieve this, we combined the effect of two anthelminthics: thiabendazole, to produce chemosterilization of adult females, and napthalophos, to expel adult worms fr...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00531638
更新日期:1988-01-01 00:00:00